AMOXISTIM 15%

AMOXISTIM 15% is an antibacterial drug of the penicillin group.

Amoxicillin, which is part of the drug, is a semi-synthetic antibiotic of the penicillin series and has a wide spectrum of antimicrobial action against most gram-positive and gram-negative microorganisms, including Campylobacter, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Escherichia coli, Listeria monocytogenes, Staphylococcus spp., Haemophilus spp.,Pasteurella spp., Salmonella spp., Streptococcus spp.

The mechanism of antibacterial action of the antibiotic is to suppress the functional activity of bacterial enzymes of transpeptidases involved in binding the main component of the cell wall of microorganisms - peptidoglycan. When the drug is administered intramuscularly or subcutaneously, amoxicillin trihydrate is gradually absorbed from the injection site and spreads throughout the body, reaching therapeutic concentrations in most organs and tissues. The binding of amoxicillin to plasma proteins is insignificant (about 17-20%), to a greater extent it accumulates in muscles, kidneys, liver, passes through the blood-brain barrier. The maximum concentration of the antibiotic in the blood is noted after 1-2 hours after parenteral administration and is kept at the therapeutic level in the body for at least 48 hours in cattle, sheep and pigs, and for at least 24 hours in dogs and cats.

The metabolic products of the components of the drug are excreted from the body mainly with urine and to a lesser extent with milk and bile unchanged.

AMOXISTIM 15% is used for cattle, sheep and pigs once intramuscularly or subcutaneously, for dogs and cats - subcutaneously at a dose of 1 ml per 10 kg of animal weight. If necessary, the drug is re-administered to cattle, sheep and pigs after 48 hours, dogs and cats - after 24 hours.

The maximum volume of suspension for administration in one place should not exceed: cattle - 20 ml, sheep - 4 ml, pigs - 5 ml, dogs - 2.5 ml, cats - 1 ml. After administration of the drug, the injection site should be massaged. Before use, the bottle with the drug must be thoroughly shaken.

Symptoms of overdose in animals may be manifested by depression, disorders of the gastrointestinal tract, swelling at the injection site. The peculiarities of the drug's action during its first use and cancellation were not revealed. Skipping the next dose of the drug should be avoided, as this may lead to a decrease in therapeutic effectiveness. If one or more doses of the drug are missed, its use is resumed in the same dosages and according to the same scheme.

When using the drug in accordance with this instruction, side effects and complications are usually not observed. In case of allergic reactions, the use of the drug is discontinued and, if necessary, desensitizing therapy is prescribed.

AMOXISTIM 15% should not be used simultaneously with bacteriostatic drugs, antibiotics of the group ?-lactam, as well as mix it in one syringe with other medications.

Slaughter of animals for meat is allowed 28 days after the last injection of the drug. The meat of animals forcibly killed before the expiration of the specified period can be used as fodder for fur-bearing animals.

Milk obtained from cows during the period of application and within 96 hours after the last administration of the drug is prohibited from being used for food purposes. Milk obtained earlier than the deadline can be used after boiling in animal feed.

Contraindications:

Contraindication for the use of the drug is individual hypersensitivity to penicillin antibiotics and other components of the drug (including in the anamnesis).

Personal prevention measures:

When using AMOXISTIM 15%, it is necessary to observe the general rules of personal hygiene and safety provided for when working with medicines. While working with the drug, it is forbidden to drink, smoke and eat. At the end of the work, wash your face and hands thoroughly with soap.

People with hypersensitivity to the components of AMOXISTIM 15% should avoid direct contact with the drug. If the drug accidentally gets on the skin or mucous membranes, it must be rinsed with plenty of water.

In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (have the instructions for the use of the drug or label with you).

Empty bottles from under the drug are prohibited from being used for household purposes, they are subject to disposal with household waste.

AMOXISTIM 15% is produced packaged in glass or polymer vials, capped with rubber stoppers, reinforced with aluminum caps. Each consumer package is provided with instructions for use.

AMOXISTIM 15% is stored in the manufacturer's closed packaging, separately from food and feed, in a dry place protected from light, at a temperature from 5 ° C to 25 ° C.

The shelf life of the drug, subject to storage conditions in a closed package, is 2 years from the date of production, after opening the bottle - no more than 28 days.

It is forbidden to use the drug after the expiration date.

AMOXISTIM 15% should be stored in places inaccessible to children.

Unused medicinal product is disposed of in accordance with the requirements of the legislation.