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Trade name of the drug: ENERGOSTIM 5% (Enrostim 5%).

International nonproprietary name: enrofloxacin.

The preparation in 1 ml as an active substance contains: enrofloxacin base - 50 mg, and as auxiliary substances: n-butanol - 30 mg, potassium hydroxide – 9 mg, water for injection - up to 1 ml.

ENROSTIM 5% is produced packaged in glass vials and polymer containers of 10 ml, 50 ml, 100 ml, 250 ml and 500 ml.

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Price on request
Dosage form
Solution for injection
Transparent yellowish liquid
Pharmacological properties

ENROSTIM 5% refers to antibacterial drugs from the fluoroquinolone group.

Enrofloxacin, which is part of the drug, has a wide spectrum of antibacterial and antimycoplasmic effects, inhibits the growth and development of gram-positive and gram-negative bacteria, including: E.coli, Haemophilus, Klebsiella, Pasteurella, Pseudomonas, Proteus, Bordetella, Brucella, Chlamydia, Enterobacter, Campylobacter, Erysipelothris, Corynebacterium, Staphylococcus, Streptococcus, Actinobacillus, Clostridium, Bacteroides, Fusobacterium, Salmjnella and Mycoplasma spp.

The mechanism of action of enrofloxacin is based on the ability to inhibit the activity of the gyrase enzyme, which ensures DNA replication in a bacterial cell. It acts bactericidal on the microbial cell. Enrofloxacin is active against gram-positive and gram-negative bacteria of the following species:

With parenteral administration into the body, enrofloxacin is rapidly absorbed into the blood and penetrates into almost all organs and tissues, reaching a maximum concentration 20-30 minutes after administration. After a single injection, the therapeutic concentration of enrofloxacin remains in the body for 24 hours. Enrofloxacin is partially metabolized into ciprofloxacin and is excreted from the body mainly in the urine.

ENROSTIM 5% by the degree of exposure to the body refers to moderately dangerous substances (hazard class 3 GOST 12.1.007-76), in recommended doses is well tolerated by animals, does not have embryotoxic, teratogenic and hepatotoxic properties.

Application procedure

Enrostim 5% is used in cattle, pigs, dogs, cats and rabbits for the treatment of respiratory organs, gastrointestinal tract, genitourinary system, septicemia, colibacteriosis, salmonellosis, streptococcosis, bacterial and enzootic pneumonia, atrophic rhinitis, mastitis-metritis-agalactia syndrome, mixed infections, secondary infections in viral diseases and other diseases caused by microorganisms sensitive to fluoroquinolones.

Contraindication to use is hypersensitivity of the animal to the components of the drug. It is not allowed to use, for females during pregnancy and lactation, for animals with severe disorders of the development of cartilage tissue, with lesions of the nervous system accompanied by convulsions, as well as for puppies of dogs and kittens until the end of the growth period.

ENROSTIM 5% is administered subcutaneously to animals (except pigs), once a day for 3-5 days, the drug is administered intramuscularly to pigs 1 time a day for 3-5 days, and in the treatment of mastitis-metritis-agalactia of sows for 1-2 days.

ENROSTIM 5% is administered to animals in the following doses:

CATTLE 1 ml per 20 kg of animal weight
Pigs 1 ml per 20 kg of animal weight
Dogs, cats, rabbits 1 ml per 10 kg of animal weight

For dogs and cats with chronic and severe diseases, the course of application of the drug can be extended up to 10 days.

Due to a possible pain reaction, the drug should not be administered in one place to large animals in a volume exceeding 5 ml and to small animals in a volume exceeding 2.5 ml.

With an overdose of the drug, the animal may experience a decrease in appetite, depression, vomiting, diarrhea.


The peculiarities of the action during the first use of the drug and its cancellation were not revealed.

Omissions should be avoided when administering the next dose of the drug, as this may lead to a decrease in effectiveness. If one dose is missed, the use of the drug is resumed at the same dose according to the same scheme.

When using ENROSTIM 5% in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. With increased individual sensitivity of the animal to fluoroquinolones and the development of allergic reactions, the use of the drug is discontinued and desensitizing therapy is carried out.

It is not recommended to use the drug simultaneously with chloramphenicol, macrolides, theophylline or with nonsteroidal anti-inflammatory drugs.

Slaughter of animals for meat is allowed no earlier than 14 days after the last use of the drug. The meat of animals forcibly killed before the expiration of the specified period can be used for feeding fur-bearing animals or for the production of meat and bone meal.

Personal prevention measures:

When working with ENROSTIM 5%, the general rules of personal hygiene and safety provided for when working with medicines should be observed. At the end of the work, hands should be washed with warm water and soap.

In case of accidental contact of the drug with the skin or mucous membranes of the eye, they should be immediately rinsed with plenty of water.

People with hypersensitivity to the components of the drug should avoid direct contact with ENROSTIM In case of allergic reactions or accidental ingestion of the drug into the human body, should immediately contact a medical institution (have the instructions for the use of the drug or label with you).

Empty bottles from under the drug are prohibited from being used for household purposes, they are subject to disposal with household waste.

Expiration dates and storage

The drug is stored in the manufacturer's closed packaging, separately from food and feed, in a dry place protected from direct sunlight at a temperature from 5 ° C to 25 ° C.

The shelf life of ENROSTIM is 5%, subject to storage conditions in a closed package – 3 years from the date of production, after opening the bottle – 30 days.

It is forbidden to use the 5% ENERGOSTIM after the expiration date.

Unused medicinal product is disposed of in accordance with the requirements of the legislation.

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