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EYMESTAT 2.5%

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International nonproprietary name: toltrazuril.


EIMESTAT 2.5% in 1 ml as an active ingredient contains toltrazuril - 25 mg, as well as auxiliary components - triethanolamine - 300 mg and propylene glycol - up to 1 ml.


In appearance, the drug is a transparent liquid from colorless to yellow-brown (opalescence is allowed).


The drug is produced packaged in containers made of polymer material of 100, 300, 1000, 3000 and 5000 ml with screw-on lids with a control ring of the first opening.

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Price on request
Type
Antiparasitic agent
Dosage form
Solution for oral use
Packing
1L; 5L
Pharmacological properties

EYMESTAT 2.5% is an anticoccidium drug for the treatment and prevention of coccidiosis in poultry.


Toltrazuril, which is part of the drug, is a synthetic substance that belongs to the triazintrione group, has a wide spectrum of anticoccidial action and a high degree of safety. Toltrazuril is effective against all types of parasitic coccidia in birds at the stages of intracellular development of parasites, including E. acervulina, E. brunetti, E. necatrix, E. mitis, E. adenoides, E. meleagrimitis, E. anceris, E. truncata, E. rgaesoh, including strains resistant to other anticoccidial drugs.


Toltrazuril, blocking respiratory enzymes of coccidia, has a damaging effect on mitochondria and the processes of division of the coccidia nucleus, disrupting the formation of macrogametocytes. After oral administration, toltrazuril is slowly absorbed and has a coccidiocidal effect on the mucous and submucosal membranes of the gastrointestinal tract.


The drug does not violate the formation of immunity against coccidiosis, it is well tolerated by poultry.


Toltrazuril is excreted from the body mainly unchanged, as well as in the form of metabolites with droppings.

Application procedure
EIMESTAT 2.5% is prescribed to poultry with coccidiosis for therapeutic and prophylactic purposes, when a critical level of coccidia content in the litter is reached (10-20 thousand / g), as well as when clinical signs of the disease appear. The drug is used to treat coccidiosis of chickens caused by E. acervulina, E. brunetti, E. maxima, E. necatrix, E. tenella, E. mitis; coccidiosis of turkeys caused by infection with E. adenoides, E. meleagrimitis; coccidiosis of geese and ducks caused by infection with E. anseris, E. truncata.

EYMESTAT 2.5% is applied to poultry with water for drinking two days in a row at a dose of 7 mg of toltrazuril (DV) per 1 kg of live weight (28 ml of EYMESTAT 2.5% per 100 kg of poultry weight), which is equivalent to:

In case of severe infections, the course of treatment can be repeated after 5 days.

During the application of EYMESTAT 2.5%, the therapeutic solution should be the only source of drinking water for poultry. The drug retains its activity in a diluted solution for 48 hours.

EYMESTAT 2.5% is compatible with coccidiostatics and amoebocidal drugs. The drug is compatible with feed additives, vitamins and medicines for poultry.

Warnings:

Slaughter of broilers for meat is allowed no earlier than 14 days, geese and ducks no earlier than 16 days after the last use of the drug. In case of forced slaughter before the deadline, the meat can be used as food for carnivores.

The drug is not prescribed to poultry with serious liver or kidney dysfunction.

IT is FORBIDDEN TO USE EYMESTAT 2.5% to LAYING HENS, due to the accumulation of the drug in eggs.

Shelf life and storage conditions

The drug is stored in a tightly closed manufacturer's packaging in a dry, light-protected place, at a temperature from 0 ° C to 25 ° C, separately from food and feed.

EIMESTAT 2.5% should be stored in places inaccessible to children.

The shelf life of the drug, subject to storage conditions in the manufacturer's closed packaging, is 5 years from the date of production, after the package is opened - 3 months.

It is forbidden to use EIMESTAT 2.5% after the expiration date.

The unused drug is disposed of in accordance with the requirements of the legislation.

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